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The Growth Factor Authority

The Growth Factor Authority

 

Our growth factors have revolutionized skincare and helped millions of people achieve healthier, younger-looking skin.

SkinMedica®  is the most studied, the most awarded, and the most respected name in growth factor skincare and has been for over 20 years.*

*Clinical studies and publications include the full portfolio of growth factor products, including SkinMedica® and Regenica. From 2010 to 2022 for select SkinMedica growth factor products only.

What are Growth Factors?

What Are Growth Factors?

They're proteins your body naturally produces that:
  • Maintain firmness and elasticity in the skin
  • Support healthy skin tone and texture
  • Play an important role in skin repair and recovery
  • Decrease as you age

A Legacy of Results

  • In 2001, we launched the first-ever topical growth factor product: TNS Recovery Complex® 
  • We've continued to evolve by introducing our most innovative growth factor product yet: TNS®  Advanced+ Serum
A Legacy of Results

In  a clinical study, TNS Advanced+ Serum patients:

Felt they looked up to 6 years younger after 12 weeks*

Saw visible  improvement in coarse wrinkles and fine lines in as little as 2 weeks

Noticed improved appearance of sagging skin after 8 weeks

Had progressive improvement over 24 weeks

*According to a third-party, validated psychometric scale.

Shop Our Growth Factor Collection 

Reduce the appearance of fine lines, wrinkles, and other signs of aging with 2 of our best-selling products.

TNS® Advanced+ Serum
Best Sellers

TNS® Advanced+ Serum

$295.00
TNS Recovery Complex®

TNS Recovery Complex®

$230.00

Dramatic,

Age-Defying Benefits

Baseline

Baseline

Week 24

Week 24

FEMALE, AGE 68, FITZPATRICK SKIN TYPE II

Unretouched photos taken with standard lighting. Individual results may vary. 

*According to a third-party, validated psychometric scale.

Proof is in the Science

Explore peer-reviewed publications that show the impact of growth factors
    1. Fitzpatrick RE, Rostan, EF. Reversal of photodamage with topical growth factors: a pilot study. J Cosmet Laser Ther. 2003:5:25-34.
    2. Fitzpatrick RE. Treatment of photodamaged and aging skin with a unique cream: 3 Case reports. Cosmet Dermatol. 2004; 17(9):591-596.
    3. Mehta RC, Fitzpatrick RE. Endogenous growth factors as cosmeceuticals. Dermatol Ther. 2007;Sep-Oct;20(5):350-9. .
    4. Mehta RC, Smith SR, Grove GL, et al. Reduction in facial photodamage by a topical growth factor product. J Drugs Dermatol. 2008;7864-871. .
    5. Trookman NS, Rizer RL, Ford R, et al. Immediate and long-term clinical benefits of a topical treatment for facial lines and wrinkles. J Clin Aesthet Dermatol. 2009; 2(3):38-43.
    6. Sundaram H, Mehta RC, Norine JA, Kircik L, et al. Topically applied physiologically balanced growth factors: a new paradigm of skin rejuvenation. J Drugs Dermatol. 2009 May;8(5 Suppl Skin Rejuvenation):4-13.
    7. Trookman NS, Rizer RL, Ford R, et al. Clinical assessment of a combination lip treatment to restore moisturization and fullness. J Clin Aesthet Dermatol. 2009; 2(12):44-48.
    8. Atkin DH, Trookman NS, Rizer RL, et al. Combination of physiologically balanced growth factors with antioxidants for reversal of facial photodamage. J Cosmet Laser Ther. 2010; 12:14-20.
    9. Kadoya K, Makino ET, Jiang, LI, et al. Upregulation of Extracellular Matrix Genes Corroborates Clinical Efficacy of Human Fibroblast-Derived Growth Factors in Skin Rejuvenation. J Drugs Dermatol. 2017; 16(12):1190-6.
    10. Naughton GK, Jiang LI, Makino ET, et al. Targeting Multiple Hallmarks of Skin Aging: Preclinical and Clinical Efficacy of a Novel Growth Factor-Based Skin Care Serum. Dermatol Ther. 2023 Jan;13(1):169-186.
    11. Gold MH, Wilson A, Makino E, et al. Improvements in Skin Quality Parameters in Postmenopausal Participants After Use of Topical Growth Factor Serum. J Cosmet Dermatol. 2023 Jan;22(1):236-244.
    12. Goldman MP, Boen M, Deaver J, et al. Effects of a Topical Growth Factor Regimen Following Pre-elected Cosmetic Facial Injection Procedures. J Drugs Dermatol. 2023 Jan 1;22(1):9-15.
    13. Kellar RS, Hubka M, Rheins LA, et al. Hypoxic conditioned culture medium from fibroblasts grown under embryonic-like conditions supports healing following post-laser resurfacing. J Cosmetic Derm. 2009; 8(3):190-196.
    14. Pinney E, Zimber M, Schenone A, et al. Human Embryonic-like ECM (hECM) Stimulates Proliferation and Differentiation in Stem Cells While Killing Cancer Cells. Int J Stem Cells 2011; 4(1):70-75.
    15. Zimber MP, Mansbridge JN, Taylor M, et al. Human cell-conditioned media produced under embryonic-like conditions result in improved healing time after laser resurfacing. Aesthetic Plast Surg. 2012; 36(2):431-437.
    16. Bruce S, Karnik J, Dryer L, et al. Anti-aging proof of concept study: results and summary. J Drugs Dermatol. 2014; 13(9):1074-1081.
    17. Sundaram H, Gold M, Waldorf H, et al. Pilot, Multicenter, Open-Label Evaluation of Safety, Tolerability and Efficacy of a Novel, Topical Multipotent Growth Factor Formulation for the Periorbital Region. J Drugs Dermatol. 2015; 14(12):1410-1417.
    18. Draelos ZD, Karnik J, Naughton G. The Anti-Aging Effects of Low Oxygen Tension Generated Multipotent Growth Factor Containing Serum. J Drugs Dermatol. 2017; 16(1):30-34.